Synthetic mRNA produces protein in cultured cells

Researchers built mRNA entirely from scratch in the lab, rather than extracting it from cells, then used positively charged fat molecules to carry it into cultured cells. The cells produced the exact protein the synthetic mRNA coded for. This decoupled the technology from biological extraction. Once mRNA could be manufactured on demand, the door opened to designing it for any protein a researcher wanted a cell to make, not just ones nature already provided.