Timeline milestone
Chemotherapy Cures a Metastatic Solid Tumour
From How Cancer Treatment Became Personal: From Chemotherapy to Precision Immunotherapy
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Clinical Milestone
Chemotherapy Cures a Metastatic Solid Tumour
Methotrexate produced durable cures in gestational choriocarcinoma, proving that systemic drugs could sometimes eradicate metastatic cancer.
This was a decisive change from temporary tumour shrinkage. The result did not mean all solid tumours were equally vulnerable, but it established cure as a realistic objective for selected cancers and encouraged combination regimens designed to prevent resistance.
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