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CRISPR is shown to provide microbial immunity
From From Bacterial Defence to Medicine: The CRISPR Gene-Editing Revolution
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Research
CRISPR is shown to provide microbial immunity
Adding viral sequences to bacterial CRISPR arrays changed resistance to later infection.
Researchers inserted fragments of viral DNA into bacterial CRISPR arrays and showed that those changes altered resistance to later infection. The experiment provided direct evidence that the system stores a genetic memory of past invaders and uses it to recognise them again. CRISPR was therefore not merely an unusual DNA pattern; it was part of an adaptive microbial immune system.
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